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Meso Scale Diagnostics LLC v-plex plus human biomarker 54-plex kit
V Plex Plus Human Biomarker 54 Plex Kit, supplied by Meso Scale Diagnostics LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/v-plex+human+biomarker+54-plex+kit/v+plex+human+biomarker+54+plex+kit/pm39775044-205-13-19
Average 90 stars, based on 1 article reviews
v-plex plus human biomarker 54-plex kit - by Bioz Stars, 2026-09
90/100 stars

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Biomarker Discovery:

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week-a prospective cohort study.
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [19], the panel was excluded).

Article Title: JAK inhibition decreases the autoimmune burden in Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12-25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (HTP cohort) or U-PLEX Human Biomarker Group 1 71-Plex and V-PLEX Human Vascular Injury Panel 2 Kits (clinical trial cohort) on a MESO QuickPlex SQ 120 instrument.

Article Title: Impact of CCR5Δ32 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donors.
Article Snippet: A total of 47 inflammatory biomarkers were measured using the Meso Scale Discovery (MSD) V-PLEX Human Biomarker 54-plex kit among a subgroup of DBDS participants termed ‘The 10K Inflammatory Biomarker Cohort’, including a chemokine panel of ten analytes (Supplementary Table S1).

Article Title: Longitudinal metabolite and protein trajectories prior to diabetes mellitus diagnosis in Danish blood donors: a nested case–control study
Article Snippet: We measured the concentration of 54 proteins using the V-PLEX metabolic panel 1 human kit and the V-PLEX human biomarker 54-plex kit (Meso Scale Diagnostics, USA) for 2025 samples (ESM Table ).

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week—a prospective cohort study
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [ ], the panel was excluded).

Article Title: Dissecting depression symptoms: Multi-omics clustering uncovers immune-related subgroups and cell-type specific dysregulation.
Article Snippet: 209 2.3.3 Immune marker measurements 210 We used the V-PLEX Human Biomarker 54-Plex Kit (Meso Scale Diagnostics (MSD), 211 Rockville, USA, Cat. No. K15248G-2) to measure immune markers in plasma, following the 212 manufacturer’s instructions and including three internal controls run in duplicate to assess status n age female BMI major depression or dysthymia diagnosis BDI-II psychotropic drugs case 237 38.8 (13.3) 58% (138) 25 (5.2) 81% (192) 23.6 (13.2) 43% (103) control without a DSM-IV diagnosis 36 31.4 (9.4) 61% (22) 23.7 (2.8) 0% (0) 2 (2.9) 0% (0) 7 213 the coefficient of variation (Table S3).

Article Title: Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12–25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (Cat # K15248D) on a MESO QuickPlex SQ 120 instrument.

Article Title: The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy
Article Snippet: A multiplex electrochemiluminescence assay (V-Plex Human Biomarker 54-Plex Kit, Meso Scale Discovery) was used according to manufacturer’s instructions.

Chemotaxis Assay:

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week-a prospective cohort study.
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [19], the panel was excluded).

Article Title: JAK inhibition decreases the autoimmune burden in Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12-25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (HTP cohort) or U-PLEX Human Biomarker Group 1 71-Plex and V-PLEX Human Vascular Injury Panel 2 Kits (clinical trial cohort) on a MESO QuickPlex SQ 120 instrument.

Article Title: Impact of CCR5Δ32 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donors.
Article Snippet: A total of 47 inflammatory biomarkers were measured using the Meso Scale Discovery (MSD) V-PLEX Human Biomarker 54-plex kit among a subgroup of DBDS participants termed ‘The 10K Inflammatory Biomarker Cohort’, including a chemokine panel of ten analytes (Supplementary Table S1).

Article Title: Longitudinal metabolite and protein trajectories prior to diabetes mellitus diagnosis in Danish blood donors: a nested case–control study
Article Snippet: We measured the concentration of 54 proteins using the V-PLEX metabolic panel 1 human kit and the V-PLEX human biomarker 54-plex kit (Meso Scale Diagnostics, USA) for 2025 samples (ESM Table ).

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week—a prospective cohort study
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [ ], the panel was excluded).

Article Title: Dissecting depression symptoms: Multi-omics clustering uncovers immune-related subgroups and cell-type specific dysregulation.
Article Snippet: 209 2.3.3 Immune marker measurements 210 We used the V-PLEX Human Biomarker 54-Plex Kit (Meso Scale Diagnostics (MSD), 211 Rockville, USA, Cat. No. K15248G-2) to measure immune markers in plasma, following the 212 manufacturer’s instructions and including three internal controls run in duplicate to assess status n age female BMI major depression or dysthymia diagnosis BDI-II psychotropic drugs case 237 38.8 (13.3) 58% (138) 25 (5.2) 81% (192) 23.6 (13.2) 43% (103) control without a DSM-IV diagnosis 36 31.4 (9.4) 61% (22) 23.7 (2.8) 0% (0) 2 (2.9) 0% (0) 7 213 the coefficient of variation (Table S3).

Article Title: Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12–25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (Cat # K15248D) on a MESO QuickPlex SQ 120 instrument.

Article Title: The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy
Article Snippet: A multiplex electrochemiluminescence assay (V-Plex Human Biomarker 54-Plex Kit, Meso Scale Discovery) was used according to manufacturer’s instructions.

Multiplex Assay:

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week-a prospective cohort study.
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [19], the panel was excluded).

Article Title: JAK inhibition decreases the autoimmune burden in Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12-25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (HTP cohort) or U-PLEX Human Biomarker Group 1 71-Plex and V-PLEX Human Vascular Injury Panel 2 Kits (clinical trial cohort) on a MESO QuickPlex SQ 120 instrument.

Article Title: Impact of CCR5Δ32 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donors.
Article Snippet: A total of 47 inflammatory biomarkers were measured using the Meso Scale Discovery (MSD) V-PLEX Human Biomarker 54-plex kit among a subgroup of DBDS participants termed ‘The 10K Inflammatory Biomarker Cohort’, including a chemokine panel of ten analytes (Supplementary Table S1).

Article Title: Longitudinal metabolite and protein trajectories prior to diabetes mellitus diagnosis in Danish blood donors: a nested case–control study
Article Snippet: We measured the concentration of 54 proteins using the V-PLEX metabolic panel 1 human kit and the V-PLEX human biomarker 54-plex kit (Meso Scale Diagnostics, USA) for 2025 samples (ESM Table ).

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week—a prospective cohort study
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [ ], the panel was excluded).

Article Title: Dissecting depression symptoms: Multi-omics clustering uncovers immune-related subgroups and cell-type specific dysregulation.
Article Snippet: 209 2.3.3 Immune marker measurements 210 We used the V-PLEX Human Biomarker 54-Plex Kit (Meso Scale Diagnostics (MSD), 211 Rockville, USA, Cat. No. K15248G-2) to measure immune markers in plasma, following the 212 manufacturer’s instructions and including three internal controls run in duplicate to assess status n age female BMI major depression or dysthymia diagnosis BDI-II psychotropic drugs case 237 38.8 (13.3) 58% (138) 25 (5.2) 81% (192) 23.6 (13.2) 43% (103) control without a DSM-IV diagnosis 36 31.4 (9.4) 61% (22) 23.7 (2.8) 0% (0) 2 (2.9) 0% (0) 7 213 the coefficient of variation (Table S3).

Article Title: Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12–25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (Cat # K15248D) on a MESO QuickPlex SQ 120 instrument.

Article Title: The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy
Article Snippet: A multiplex electrochemiluminescence assay (V-Plex Human Biomarker 54-Plex Kit, Meso Scale Discovery) was used according to manufacturer’s instructions.

Electrochemiluminescence:

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week-a prospective cohort study.
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [19], the panel was excluded).

Article Title: JAK inhibition decreases the autoimmune burden in Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12-25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (HTP cohort) or U-PLEX Human Biomarker Group 1 71-Plex and V-PLEX Human Vascular Injury Panel 2 Kits (clinical trial cohort) on a MESO QuickPlex SQ 120 instrument.

Article Title: Impact of CCR5Δ32 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donors.
Article Snippet: A total of 47 inflammatory biomarkers were measured using the Meso Scale Discovery (MSD) V-PLEX Human Biomarker 54-plex kit among a subgroup of DBDS participants termed ‘The 10K Inflammatory Biomarker Cohort’, including a chemokine panel of ten analytes (Supplementary Table S1).

Article Title: Longitudinal metabolite and protein trajectories prior to diabetes mellitus diagnosis in Danish blood donors: a nested case–control study
Article Snippet: We measured the concentration of 54 proteins using the V-PLEX metabolic panel 1 human kit and the V-PLEX human biomarker 54-plex kit (Meso Scale Diagnostics, USA) for 2025 samples (ESM Table ).

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week—a prospective cohort study
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [ ], the panel was excluded).

Article Title: Dissecting depression symptoms: Multi-omics clustering uncovers immune-related subgroups and cell-type specific dysregulation.
Article Snippet: 209 2.3.3 Immune marker measurements 210 We used the V-PLEX Human Biomarker 54-Plex Kit (Meso Scale Diagnostics (MSD), 211 Rockville, USA, Cat. No. K15248G-2) to measure immune markers in plasma, following the 212 manufacturer’s instructions and including three internal controls run in duplicate to assess status n age female BMI major depression or dysthymia diagnosis BDI-II psychotropic drugs case 237 38.8 (13.3) 58% (138) 25 (5.2) 81% (192) 23.6 (13.2) 43% (103) control without a DSM-IV diagnosis 36 31.4 (9.4) 61% (22) 23.7 (2.8) 0% (0) 2 (2.9) 0% (0) 7 213 the coefficient of variation (Table S3).

Article Title: Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12–25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (Cat # K15248D) on a MESO QuickPlex SQ 120 instrument.

Article Title: The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy
Article Snippet: A multiplex electrochemiluminescence assay (V-Plex Human Biomarker 54-Plex Kit, Meso Scale Discovery) was used according to manufacturer’s instructions.

Biomarker Assay:

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week-a prospective cohort study.
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [19], the panel was excluded).

Article Title: JAK inhibition decreases the autoimmune burden in Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12-25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (HTP cohort) or U-PLEX Human Biomarker Group 1 71-Plex and V-PLEX Human Vascular Injury Panel 2 Kits (clinical trial cohort) on a MESO QuickPlex SQ 120 instrument.

Article Title: Impact of CCR5Δ32 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donors.
Article Snippet: A total of 47 inflammatory biomarkers were measured using the Meso Scale Discovery (MSD) V-PLEX Human Biomarker 54-plex kit among a subgroup of DBDS participants termed ‘The 10K Inflammatory Biomarker Cohort’, including a chemokine panel of ten analytes (Supplementary Table S1).

Article Title: Longitudinal metabolite and protein trajectories prior to diabetes mellitus diagnosis in Danish blood donors: a nested case–control study
Article Snippet: We measured the concentration of 54 proteins using the V-PLEX metabolic panel 1 human kit and the V-PLEX human biomarker 54-plex kit (Meso Scale Diagnostics, USA) for 2025 samples (ESM Table ).

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week—a prospective cohort study
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [ ], the panel was excluded).

Article Title: Dissecting depression symptoms: Multi-omics clustering uncovers immune-related subgroups and cell-type specific dysregulation.
Article Snippet: 209 2.3.3 Immune marker measurements 210 We used the V-PLEX Human Biomarker 54-Plex Kit (Meso Scale Diagnostics (MSD), 211 Rockville, USA, Cat. No. K15248G-2) to measure immune markers in plasma, following the 212 manufacturer’s instructions and including three internal controls run in duplicate to assess status n age female BMI major depression or dysthymia diagnosis BDI-II psychotropic drugs case 237 38.8 (13.3) 58% (138) 25 (5.2) 81% (192) 23.6 (13.2) 43% (103) control without a DSM-IV diagnosis 36 31.4 (9.4) 61% (22) 23.7 (2.8) 0% (0) 2 (2.9) 0% (0) 7 213 the coefficient of variation (Table S3).

Article Title: Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12–25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (Cat # K15248D) on a MESO QuickPlex SQ 120 instrument.

Article Title: The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy
Article Snippet: A multiplex electrochemiluminescence assay (V-Plex Human Biomarker 54-Plex Kit, Meso Scale Discovery) was used according to manufacturer’s instructions.

Marker:

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week-a prospective cohort study.
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [19], the panel was excluded).

Article Title: JAK inhibition decreases the autoimmune burden in Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12-25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (HTP cohort) or U-PLEX Human Biomarker Group 1 71-Plex and V-PLEX Human Vascular Injury Panel 2 Kits (clinical trial cohort) on a MESO QuickPlex SQ 120 instrument.

Article Title: Impact of CCR5Δ32 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donors.
Article Snippet: A total of 47 inflammatory biomarkers were measured using the Meso Scale Discovery (MSD) V-PLEX Human Biomarker 54-plex kit among a subgroup of DBDS participants termed ‘The 10K Inflammatory Biomarker Cohort’, including a chemokine panel of ten analytes (Supplementary Table S1).

Article Title: Longitudinal metabolite and protein trajectories prior to diabetes mellitus diagnosis in Danish blood donors: a nested case–control study
Article Snippet: We measured the concentration of 54 proteins using the V-PLEX metabolic panel 1 human kit and the V-PLEX human biomarker 54-plex kit (Meso Scale Diagnostics, USA) for 2025 samples (ESM Table ).

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week—a prospective cohort study
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [ ], the panel was excluded).

Article Title: Dissecting depression symptoms: Multi-omics clustering uncovers immune-related subgroups and cell-type specific dysregulation.
Article Snippet: 209 2.3.3 Immune marker measurements 210 We used the V-PLEX Human Biomarker 54-Plex Kit (Meso Scale Diagnostics (MSD), 211 Rockville, USA, Cat. No. K15248G-2) to measure immune markers in plasma, following the 212 manufacturer’s instructions and including three internal controls run in duplicate to assess status n age female BMI major depression or dysthymia diagnosis BDI-II psychotropic drugs case 237 38.8 (13.3) 58% (138) 25 (5.2) 81% (192) 23.6 (13.2) 43% (103) control without a DSM-IV diagnosis 36 31.4 (9.4) 61% (22) 23.7 (2.8) 0% (0) 2 (2.9) 0% (0) 7 213 the coefficient of variation (Table S3).

Article Title: Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12–25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (Cat # K15248D) on a MESO QuickPlex SQ 120 instrument.

Article Title: The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy
Article Snippet: A multiplex electrochemiluminescence assay (V-Plex Human Biomarker 54-Plex Kit, Meso Scale Discovery) was used according to manufacturer’s instructions.

Clinical Proteomics:

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week-a prospective cohort study.
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [19], the panel was excluded).

Article Title: JAK inhibition decreases the autoimmune burden in Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12-25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (HTP cohort) or U-PLEX Human Biomarker Group 1 71-Plex and V-PLEX Human Vascular Injury Panel 2 Kits (clinical trial cohort) on a MESO QuickPlex SQ 120 instrument.

Article Title: Impact of CCR5Δ32 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donors.
Article Snippet: A total of 47 inflammatory biomarkers were measured using the Meso Scale Discovery (MSD) V-PLEX Human Biomarker 54-plex kit among a subgroup of DBDS participants termed ‘The 10K Inflammatory Biomarker Cohort’, including a chemokine panel of ten analytes (Supplementary Table S1).

Article Title: Longitudinal metabolite and protein trajectories prior to diabetes mellitus diagnosis in Danish blood donors: a nested case–control study
Article Snippet: We measured the concentration of 54 proteins using the V-PLEX metabolic panel 1 human kit and the V-PLEX human biomarker 54-plex kit (Meso Scale Diagnostics, USA) for 2025 samples (ESM Table ).

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week—a prospective cohort study
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [ ], the panel was excluded).

Article Title: Dissecting depression symptoms: Multi-omics clustering uncovers immune-related subgroups and cell-type specific dysregulation.
Article Snippet: 209 2.3.3 Immune marker measurements 210 We used the V-PLEX Human Biomarker 54-Plex Kit (Meso Scale Diagnostics (MSD), 211 Rockville, USA, Cat. No. K15248G-2) to measure immune markers in plasma, following the 212 manufacturer’s instructions and including three internal controls run in duplicate to assess status n age female BMI major depression or dysthymia diagnosis BDI-II psychotropic drugs case 237 38.8 (13.3) 58% (138) 25 (5.2) 81% (192) 23.6 (13.2) 43% (103) control without a DSM-IV diagnosis 36 31.4 (9.4) 61% (22) 23.7 (2.8) 0% (0) 2 (2.9) 0% (0) 7 213 the coefficient of variation (Table S3).

Article Title: Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12–25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (Cat # K15248D) on a MESO QuickPlex SQ 120 instrument.

Article Title: The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy
Article Snippet: A multiplex electrochemiluminescence assay (V-Plex Human Biomarker 54-Plex Kit, Meso Scale Discovery) was used according to manufacturer’s instructions.

Control:

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week-a prospective cohort study.
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [19], the panel was excluded).

Article Title: JAK inhibition decreases the autoimmune burden in Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12-25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (HTP cohort) or U-PLEX Human Biomarker Group 1 71-Plex and V-PLEX Human Vascular Injury Panel 2 Kits (clinical trial cohort) on a MESO QuickPlex SQ 120 instrument.

Article Title: Impact of CCR5Δ32 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donors.
Article Snippet: A total of 47 inflammatory biomarkers were measured using the Meso Scale Discovery (MSD) V-PLEX Human Biomarker 54-plex kit among a subgroup of DBDS participants termed ‘The 10K Inflammatory Biomarker Cohort’, including a chemokine panel of ten analytes (Supplementary Table S1).

Article Title: Longitudinal metabolite and protein trajectories prior to diabetes mellitus diagnosis in Danish blood donors: a nested case–control study
Article Snippet: We measured the concentration of 54 proteins using the V-PLEX metabolic panel 1 human kit and the V-PLEX human biomarker 54-plex kit (Meso Scale Diagnostics, USA) for 2025 samples (ESM Table ).

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week—a prospective cohort study
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [ ], the panel was excluded).

Article Title: Dissecting depression symptoms: Multi-omics clustering uncovers immune-related subgroups and cell-type specific dysregulation.
Article Snippet: 209 2.3.3 Immune marker measurements 210 We used the V-PLEX Human Biomarker 54-Plex Kit (Meso Scale Diagnostics (MSD), 211 Rockville, USA, Cat. No. K15248G-2) to measure immune markers in plasma, following the 212 manufacturer’s instructions and including three internal controls run in duplicate to assess status n age female BMI major depression or dysthymia diagnosis BDI-II psychotropic drugs case 237 38.8 (13.3) 58% (138) 25 (5.2) 81% (192) 23.6 (13.2) 43% (103) control without a DSM-IV diagnosis 36 31.4 (9.4) 61% (22) 23.7 (2.8) 0% (0) 2 (2.9) 0% (0) 7 213 the coefficient of variation (Table S3).

Article Title: Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12–25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (Cat # K15248D) on a MESO QuickPlex SQ 120 instrument.

Article Title: The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy
Article Snippet: A multiplex electrochemiluminescence assay (V-Plex Human Biomarker 54-Plex Kit, Meso Scale Discovery) was used according to manufacturer’s instructions.

Concentration Assay:

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week-a prospective cohort study.
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [19], the panel was excluded).

Article Title: JAK inhibition decreases the autoimmune burden in Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12-25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (HTP cohort) or U-PLEX Human Biomarker Group 1 71-Plex and V-PLEX Human Vascular Injury Panel 2 Kits (clinical trial cohort) on a MESO QuickPlex SQ 120 instrument.

Article Title: Impact of CCR5Δ32 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donors.
Article Snippet: A total of 47 inflammatory biomarkers were measured using the Meso Scale Discovery (MSD) V-PLEX Human Biomarker 54-plex kit among a subgroup of DBDS participants termed ‘The 10K Inflammatory Biomarker Cohort’, including a chemokine panel of ten analytes (Supplementary Table S1).

Article Title: Longitudinal metabolite and protein trajectories prior to diabetes mellitus diagnosis in Danish blood donors: a nested case–control study
Article Snippet: We measured the concentration of 54 proteins using the V-PLEX metabolic panel 1 human kit and the V-PLEX human biomarker 54-plex kit (Meso Scale Diagnostics, USA) for 2025 samples (ESM Table ).

Article Title: Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week—a prospective cohort study
Article Snippet: Inflammatory markers from the second trimester malformation scan serum sample were measured using the Meso Scale Diagnostics (MSD) V-PLEX Human Biomarker 54-Plex kit, measuring 47 biomarkers involved in inflammation, chemotaxis, angiogenesis, and immune system regulation (due to poor quality observed for the TH-17 panel [ ], the panel was excluded).

Article Title: Dissecting depression symptoms: Multi-omics clustering uncovers immune-related subgroups and cell-type specific dysregulation.
Article Snippet: 209 2.3.3 Immune marker measurements 210 We used the V-PLEX Human Biomarker 54-Plex Kit (Meso Scale Diagnostics (MSD), 211 Rockville, USA, Cat. No. K15248G-2) to measure immune markers in plasma, following the 212 manufacturer’s instructions and including three internal controls run in duplicate to assess status n age female BMI major depression or dysthymia diagnosis BDI-II psychotropic drugs case 237 38.8 (13.3) 58% (138) 25 (5.2) 81% (192) 23.6 (13.2) 43% (103) control without a DSM-IV diagnosis 36 31.4 (9.4) 61% (22) 23.7 (2.8) 0% (0) 2 (2.9) 0% (0) 7 213 the coefficient of variation (Table S3).

Article Title: Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndrome
Article Snippet: Briefly, from each EDTA plasma sample, two replicates of 12–25 μL were analyzed using the Meso Scale Discovery (MSD) multiplex immunoassay platform V-PLEX Human Biomarker 54-Plex Kit (Cat # K15248D) on a MESO QuickPlex SQ 120 instrument.

Article Title: The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy
Article Snippet: A multiplex electrochemiluminescence assay (V-Plex Human Biomarker 54-Plex Kit, Meso Scale Discovery) was used according to manufacturer’s instructions.



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